Piero Barboni Selected Research

Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy)

1/2021	Therapeutic Options in Hereditary Optic Neuropathies.
3/2018	Retinal dysfunction characterizes subtypes of dominant optic atrophy.
12/2016	A neurodegenerative perspective on mitochondrial optic neuropathies.
9/2014	Early macular retinal ganglion cell loss in dominant optic atrophy: genotype-phenotype correlation.
2/2013	Idebenone treatment in patients with OPA1-mutant dominant optic atrophy.
10/2011	Retinal nerve fiber layer thickness in dominant optic atrophy measurements by optical coherence tomography and correlation with age.
5/2011	A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16.
1/2011	Defective mitochondrial adenosine triphosphate production in skeletal muscle from patients with dominant optic atrophy due to OPA1 mutations.
8/2010	Melanopsin retinal ganglion cells are resistant to neurodegeneration in mitochondrial optic neuropathies.
5/2009	Retinal ganglion cell neurodegeneration in mitochondrial inherited disorders.

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Piero Barboni Research Topics

Disease

26	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 01/2022 - 06/2002
11	Optic Nerve Diseases (Optic Neuropathy) 01/2021 - 01/2007
11	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2021 - 11/2004
10	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2009
8	Cataract (Cataracts) 11/2019 - 08/2006
6	Ganglion Cysts (Ganglion) 01/2022 - 09/2014
5	Optic Atrophy 01/2020 - 05/2009
3	Wolfram Syndrome (Syndrome, Wolfram) 01/2022 - 01/2020
3	Deafness (Deaf Mutism) 07/2015 - 05/2009
2	Atrophy 01/2021 - 01/2012
2	Papilledema 01/2018 - 08/2006
2	Ischemic Optic Neuropathy (Anterior Ischemic Optic Neuropathy) 11/2017 - 05/2008
2	Glaucoma 11/2017 - 10/2005
2	Myopia 03/2016 - 02/2011
2	Friedreich Ataxia (Friedreich's Ataxia) 05/2009 - 01/2009
1	Brain Diseases (Brain Disorder) 01/2021
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2021
1	Optic Disk Drusen (Optic Disc Drusen) 01/2021
1	Renal Insufficiency (Renal Failure) 01/2020
1	Macular Degeneration (Age-Related Maculopathy) 01/2020
1	Hemorrhage 01/2016
1	Alzheimer Disease (Alzheimer's Disease) 01/2016
1	Ischemia 01/2016
1	Cognitive Dysfunction 07/2015
1	Dementia (Dementias) 07/2015
1	Peripheral Nervous System Diseases (PNS Diseases) 07/2015
1	Mitochondrial Myopathies (Mitochondrial Myopathy) 07/2015
1	Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia) 07/2015
1	Parkinsonian Disorders (Parkinsonism) 07/2015
1	Refractive Errors (Refractive Error) 09/2014
1	Muscular Diseases (Myopathy) 08/2014
1	Deglutition Disorders (Dysphagia) 08/2014
1	Cataplexy 06/2014
1	Narcolepsy 06/2014
1	Cerebellar Ataxia, Deafness, and Narcolepsy 05/2014
1	Pathologic Dilatation (Ectasia) 11/2012
1	Disease Progression 03/2012
1	Keratoconus 10/2011
1	Lactic Acidosis 05/2009
1	Dystonia (Limb Dystonia) 05/2009
1	Hereditary Sensory and Motor Neuropathy (Dejerine Sottas Disease) 05/2009
1	Hereditary Spastic Paraplegia 05/2009
1	Hereditary Motor And Sensory Neuropathy VI 05/2009
1	Stroke (Strokes) 05/2009
1	Costeff optic atrophy syndrome 05/2009
1	MELAS Syndrome (Syndrome, MELAS) 05/2009
1	Dry Eye Syndromes (Dry Eye Syndrome) 08/2006
1	Blister (Bulla) 10/2005

Drug/Important Bio-Agent (IBA)

26	Retinaldehyde (Retinal)IBA 01/2022 - 01/2005
15	Mitochondrial DNA (mtDNA)IBA 01/2021 - 06/2002
5	idebenoneIBA 01/2021 - 09/2011
4	melanopsinIBA 01/2021 - 08/2010
4	Mitochondrial Proteins (Mitochondrial Protein)IBA 05/2011 - 11/2004
3	Pharmaceutical PreparationsIBA 01/2021 - 12/2016
3	Adenosine Triphosphate (ATP)IBA 05/2011 - 11/2004
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2021 - 05/2011
2	CalciumIBA 06/2020 - 01/2020
2	Phosphorus (Red Phosphorus)IBA 05/2011 - 01/2011
1	AntioxidantsIBA 01/2021
1	salicylhydroxamic acid (SHAM)IBA 01/2021
1	tyramine-deoxysorbitolIBA 01/2021
1	Adenosine Triphosphatases (ATPase)IBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 12/2018
1	Indocyanine Green (Cardio-Green)FDA LinkGeneric 11/2017
1	Fluorescein (Funduscein)FDA LinkGeneric 11/2017
1	Membrane Proteins (Integral Membrane Proteins)IBA 12/2016
1	Cytochromes b (Cytochrome b)IBA 08/2014
1	OrexinsIBA 06/2014
1	DNA (Cytosine-5-)-Methyltransferases (DNA (Cytosine 5) Methyltransferase)IBA 05/2014
1	alpha-tocotrienol quinoneIBA 03/2012
1	Carisoprodol (Soma)FDA LinkGeneric 01/2012
1	MelatoninIBA 08/2010
1	Glutamic Acid (Glutamate)FDA Link 05/2009
1	FrataxinIBA 01/2009
1	n-hexaneIBA 01/2007
1	SolventsIBA 01/2007
1	Mitomycin (Mitomycin-C)FDA LinkGeneric 10/2005
1	AntimetabolitesIBA 10/2005
1	NADH DehydrogenaseIBA 11/2004
1	Dynamins (Dynamin)IBA 11/2004
1	Amino Acids FDA Link 11/2004
1	GTP Phosphohydrolases (GTPases)IBA 11/2004
1	NucleotidesIBA 06/2002

Therapy/Procedure

5	Excimer Lasers 11/2019 - 02/2011
3	Lasers (Laser) 01/2022 - 02/2014
3	Intraocular Lenses (Intraocular Lens) 01/2017 - 09/2014
2	Refractive Surgical Procedures 08/2018 - 10/2011
2	Laser In Situ Keratomileusis (LASIK) 03/2016 - 08/2006
2	Intraocular Lens Implantation 04/2015 - 04/2014
1	Intravitreal Injections 01/2021
1	Transplantation 01/2020
1	Trabeculectomy (Trabeculoplasty) 10/2005